Biofilm is a thin and sturdy layer of one or more types of microorganisms that may have attached on living or non living surfaces. This 3D structure is held together by an extracellular polymeric substance. Free swimming bacteria attach to the surface by releasing extracellular polymeric substance. This helps it in binding to other cell surfaces also and making matrix. The biofilms are known to be responsible for the spread of virulence factors and antibiotic resistance markers leading to persistent infections. This approach aims to assess novel methods for the treatment of biofilm induced ailments.