Immunogenicity of any peptidic antigen may involve proinflammatory or anti-inflamatory immune response. Here, we have provided a machine learning based prediction tool for prediction of proinflamatory and antiinflamatory response of any peptide/protein antigen.
TO assist users, we have incorporated following section/tools in this web server: Peptide prediction: In this section, user can submit peptide of 4-30 amino acid length and can predict the proinflammatory property of peptides. Protein Scan: This tool enables user to identify proinflammatory regions in a full length protein/amino acid sequence. Here user can select desired length of peptide for prediction. Epitope Mapping: To assist user mapping experimentally validated proinflammatory epitopes on its query sequence, we have provided this tool. In this tool user can get the query mapped with proinflammatory epitopes and links to related assay in IEDB database. Similarity Search: In contrast to the epitope mapping module where exact matches with experimental data is seen, this tool performs Smith Watermann search of query sequence in database of experimentally validated proinflammatory epitopes.